30186-36-8

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Methoxy-phenyl)-1H-pyrrole-2-carbaldehyde serves as a key intermediate in the synthesis of pharmaceuticals. Its unique structure contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-Methoxy-phenyl)-1H-pyrrole-2-carbaldehyde is utilized as a component in the creation of agrochemicals. Its incorporation aids in the development of effective products for agricultural use.
Used in Material Science:
1-(4-Methoxy-phenyl)-1H-pyrrole-2-carbaldehyde also finds application in material science. It is used in the synthesis of novel materials with specific properties, contributing to advances in various material-related fields.
It is crucial to handle and store 1-(4-Methoxy-phenyl)-1H-pyrrole-2-carbaldehyde with care, adhering to proper safety protocols and guidelines to ensure safe usage in these industries.

InChI:InChI=1/C12H11NO2/c1-15-12-6-4-10(5-7-12)13-8-2-3-11(13)9-14/h2-9H,1H3

Upstream product

• 98-01-1 furfural 
• 104-94-9 4-methoxy-aniline 
• 1003-29-8 2-pyrrole aldehyde 
• 623-12-1 4-chloromethoxybenzene 
• 5145-71-1 1-(p-methoxyphenyl)pyrrole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 174415-45-3 (E)-2-nitro-1-(N-(4-methoxyphenyl)pyrrol-2-yl)prop-2-ene 
• 174415-39-5 ethyl 3-(N-(4-methoxyphenyl)pyrrol-2-yl)-4,5-dihydro-1H-pyrroline-2,4-dicarboxylate 
• 1245638-72-5 2-(cyclopenta-2,4-dienylidenemethyl)-1-(4-methoxyphenyl)-pyrrole 
• 88075-92-7 1-(4-methoxyphenyl)-1H-pyrrole-3-carbaldehyde 

Relevant academic research and scientific papers

A triazine-phosphite polymeric ligand bearing cage-like P,N-ligation sites: An efficient ligand in the nickel-catalyzed amination of aryl chlorides and phenols

A novel P,N-ligand was introduced for efficient Ni-catalyzed amination of aryl chlorides. Reaction of cyanuric acid (1,3,5-triazine-2,4,6-triol) and trichlorophosphine (PCl3) resulted in the production of a new porous material (TPPM) containing triazine rings with phosphite moieties in a sheet morphology. Cavities in the prepared compound create sites on the surface of the material with appropriate ligation character to coordinate with metals for catalytic purposes. The nickel-catalyzed amination of aryl chlorides and of phenols in their 2,4,6-triaryloxy-1,3,5-triazine (TAT) protected form were efficiently accomplished in the presence of this easily prepared and reusable P,N-ligand under mild reaction conditions. More importantly, TPPM was reusable for 5 iterations following this protocol without significantly decreasing in its activity.

Synthesis and preliminary cytotoxicity studies of achiral pyrrolyl-substituted titanocenes

From the reaction of various 6-pyrrolylfulvenes (3a-3d) with Super Hydride (LiBEt3H), lithiated cyclopentadienide intermediates (4a-4d) were synthesised. These intermediates were then transmetallated with titanium tetrachloride TiCl4

Synthesis of New Phenylpyrrolylpyrroles

A series of methyl or ethyl 3-(N-arylpyrrol-2-yl)-1H-pyrrole-2-carboxylates and 2,4-dicarboxylates has been synthesized using an alkyl isocyanides addition-cyclization to N-arylpyrrole derivatives such as carboxaldehydes and nitropropenes.

SYNTHESIS AND SPECTRAL PROPERTIES OF 1-ARYL-2-FORMYLPYRROLES

Various 1-aryl-2-formylpyrroles were synthesized by reaction of furfurol with substituted anilines.For p-bromo- and p-chlorophenyl substituents, the intermediate Schiff bases were isolated.