3019-86-1

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(4-hydroxyphenyl)-, sodium salt is used as a reagent in organic synthesis for the production of pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Flavor and Fragrance Industry:
In the flavor and fragrance industry, this chemical compound is utilized as a key ingredient in the creation of flavoring agents and fragrances, enhancing the sensory experience of various products.
Used in Research Laboratories:
Ethanone, 1-(4-hydroxyphenyl)-, sodium salt is employed in research settings for its antioxidant and antimicrobial properties, aiding in the study and development of new treatments and preventive measures against various diseases and infections.
Used in Food and Beverage Industry:
With potential applications in the food and beverage industry, this sodium salt derivative of acetophenone is considered for use as a preservative or flavor enhancer, improving the shelf life and taste of various consumables.
It is crucial to handle Ethanone, 1-(4-hydroxyphenyl)-, sodium salt with care and implement proper safety measures due to its potential health hazards, ensuring the well-being of both workers and consumers.

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 107167-08-8 1-bromo-1-chloropropane 
• 476360-75-5 4-i[(phenoxycarbonyl)oxy]acetophenone 

Downstream Products

• 1919-15-9 1,1',1''-(((1,3,5-triazine-2,4,6-triyl)tris(oxy))tris(benzene-4,1-diyl))tris(ethan-1-one) 
• 824956-34-5 (Et₄N)[W(O-p-C₆H₄COMe)(S₂C₂Me₂)2] 
• 824956-32-3 (Et₄N)[Mo(O-p-C₆H₄COMe)(S₂C₂Me₂)2] 
• 132948-69-7 1-[4-(2-Hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone 
• 87343-74-6 C₁₇H₁₆N₂O₄ 
• 87343-73-5 p-acetylphenyl 4-phenylallophanate 
• 10345-50-3 O-(4-acetylphenyl) N,N-dimethylcarbamothioate 
• 21200-93-1 <4-Acetyl-phenyl>-dimethyl-phosphat 
• 21054-16-0 O-<4-Acetyl-phenyl>-di-O-methyl-thiophosphat 
• 19152-55-7 1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone 
• 54888-20-9 p-acetyl-phenyl chloroformate 

Relevant academic research and scientific papers

Kinetics and mechanism of alkaline hydrolysis of Y-substituted phenyl phenyl carbonates

Second-order rate constants (kOH-) have been measured spectrophotometrically for alkaline hydrolysis of Y-substituted phenyl phenyl carbonates (2a-j) and compared with the kOH- values reported previously for the corresponding reactions of Y-substituted phenyl benzoates (1a-j). Carbonates 2a-j are 8 ～ 16 times more reactive than benzoates 1a-j. The Hammett plots correlated with σ- and σo constants exhibit many scattered points, while the Yukawa-Tsuno plot results in excellent linear correlation with ρ = 1.21 and r = 0.33. Thus, the reaction has been concluded to proceed through a concerted mechanism in which expulsion of the leaving group is advanced only a little. However, one cannot exclude a possibility that the current reaction proceeds through a forced concerted mechanism with a highly unstable intermediate.

Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment

A method of inhibiting Type 1 allergic responses in a living animal body with substituted heterocyclic amines is disclosed wherein the active agents are expressed generally by the formula which includes certain known and certain known compounds: STR1 wherein P is zero, one or two; m is one to six inclusive; A is selected from hydrogen, hydroxy or cyano; d is zero or one; Q is --CH--, CH2 -- or STR2 n is zero or one and when Q is --CH-- and n is one, a double bond is formed with one of the adjacent carbons but not both at the same time, and when n and d are zero at the same time, a double bond is formed between the α carbon and a carbon of the central heterocyclic amine ring; Ar, D and R are selected from phenyl, substituted phenyl, pyridinyl, thienyl, furanyl or naphthyl and in addition, R may have the values benzyl, substituted benzyl, cycloalkyl or loweralkyl and D may additionally have the values: 2H-1-benzopyran-2-one,4-oxo-4H-1-benzopyran-2-carboxylic acid loweralkyl ester, 2,3-dihydro-4H-1-benzopyran-4-one, 1,4-benzodioxanloweralkyl-2-yl or 1,1'-biphenyl-4-yl and the pharmaceutically acceptable salts thereof.

Nouvelles syntheses de phenyl-4 allophanates

The synthesis of eighteen alkyl or phenyl 4-phenylallophanates is described.The classical methods used for the preparation of allophanates - namely, condensation between an isocyanate and a carbamate, reaction between a urea and a carbonate, desulphurization of 3-thioallophanic acid esters - proved to be unsuitable for the synthesis of 4-phenylallophanic acid phenyl esters.Variously substituted 4-phenylallophanates can be obtained by reacting a chloroformate with a phenylurea in the presence of pyridine, which promotes the transfer of the carboxylate group.The occurence of electrondonating substituents, such as CH3, at the nitrogen atom receiving the carboxylate group promotes the reaction.The low yields observed for aliphatic esters can be accounted for by the instability of the alkyl chloroformate-pyridine complex.The structures of the derivatives synthesized was corroborated by the analysis of their n.m.r. and u.v. spectra. Non-commercial phenyl chloroformates were prepared by reacting phosgene with a sodium phenolate in the presence of anhydrous benzene.