30213-23-1Relevant academic research and scientific papers
The Enantioselective Synthesis of an Important Intermediate to the Antiviral, (-)-Carbovir
Handa, Sheetal,Earlam, George J.,Geary, Phillip J.,Hawes, John E.,Phillips, Gareth T.,et al.
, p. 1885 - 1886 (2007/10/02)
Two new routes to the important intermediate (-)-8 for the carbocyclic-based nucleosides are reported.The intermediate (-)-8 has also been synthesised in high enantiomeric excess via an enzymatic resolution of the racemic amide (+)-8 or an enzymatic enantiotopic hydrolysis of the meso diester 12.
