302329-72-2

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 302329-70-0 5-t-butyldimethylsilyloxy-3-(3'-oxobutyl)-2,4,4-trimethylcyclohex-2-enone 
• 302329-58-4 3-(3'-acetoxybutyl)-2,2,4-trimethylcyclohex-3-enol 
• 302329-65-3 5-t-butyldimethylsilyloxy-3-(3'-hydroxybutyl)-2,4,4-trimethylcyclohex-2-enone 
• 302329-60-8 acetic acid 3-[5-(tert-butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-cyclohex-1-enyl]-1-methyl-propyl ester 
• 302329-62-0 3-(3'-acetoxybutyl)-5-t-butyldimethylsilyloxy-2,4,4-trimethylcyclohex-2-enone 

Downstream Products

• 302329-74-4 5-hydroxy-3-(3'-hydroxy-3'-methylpent-4'-enyl)-2,4,4-trimethylcyclohex-2-enone 

Relevant academic research and scientific papers

Synthesis of natural oxygenated monocarbocyclic sesquiterpenoids from 6,7-epoxygeranyl acetate

Natural sesquiterpenes 5-(2',5'-epoxy-2',6',6'-trimethyl)cyclohexyl-3-methyl-1-penten-3-ol (5), cis-3-[(E)-5'-hydroxy-3'-methyl-3'-pentenyl]-2,2-dimethyl-4-methy lenecyclohexanol (elegansidiol) (6), 4-(5'-acetoxy-2',6',6'-trimethyl)cyclohex-2'-enyl-3-methyl-1-pent en-3-ol (7) and 5-acetoxy-3-(3-hydroxy-3-methylpent-4-enyl)-2,4,4-trimethylcycloh ex-2-enone (8) were prepared from 6,7-epoxygeranyl acetate (9), via (2',5'-epoxy-2',6',6'-trimethyl)cyclohexylmethyl tosylate (10), for the first time. 5 is an intermediate in the synthesis of the sesquiterpene-coumarin ether (±)-farnesiferol C (1). The preparation of suitable intermediates for synthesising related natural farnesiferol B (3) and D (4) is also reported. (C) 2000 Elsevier Science Ltd.