302554-00-3Relevant academic research and scientific papers
The reaction of dimethyl(diazomethyl)phosphonate with glycide derivatives: Synthesis of glyco-1-ynitols
Thiery,Frechou,Demailly
, p. 6337 - 6339 (2000)
Reaction of aldose derivatives with dimethyl(diazomethyl)phosphonate, generated in situ by methanolysis of dimethyl(1-diazo-2-oxopropyl)phosphonate, leads to glyco-1-ynitols derivatives. This synthesis presents two main advantages: it is a one-step synthesis, and tolerates free hydroxyl groups. (C) 2000 Elsevier Science Ltd.
Synthesis of glyco-1-ynitols via 1,1-dibromo-1-alkenes from partially and unprotected aldoses
Dolhem, Franck,Lièvre, Catherine,Demailly, Gilles
, p. 155 - 164 (2003)
We report the synthesis of 1,1-dibromo-1-alkenes from partially and unprotected aldoses and the synthesis of glyco-1-ynitols from these dibromocompounds. The 1,1-dibromo-1-alkenes were obtained by the reaction of dibromomethyl-triphenylphosphonium bromide
