302593-14-2

Upstream product

• 55135-66-5 9-bromo-9-phenyl-9H-fluorene 

Downstream Products

• 302593-16-4 Methyl 2-deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-L-idonate 
• 302593-18-6 methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate 
• 302593-25-5 2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol 
• 302593-20-0 methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate 
• 302593-29-9 Methyl 2-deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-6-methanesulfonyl-L-idonate 

Relevant academic research and scientific papers

A Short and Efficient Synthesis of 2R,3R,4R-3,4-Dihydroxyproline 1,4-Dideoxy-1,4-imino-L-xylitol, 2R,3R,4R,5S-3,4,5-Trihydroxypipecolic Acid, and 1,5-Dideoxy-1,5-imino-L-iditol

The syntheses of pyrrolidine alkaloids (-)-1 and (+)-3 were accomplished in 47 percent and 60 percent overall yield from 2-azido-2-deoxy-L-idonate 5, while piperidine alkaloids (-)-2 and (+)-4 were obtained in 51 percent and 53 percent overall yield from the same starting material. Key step includes iodine promoted one-pot cyclization, and selective deprotection of isopropylidene and 9-phenylfluoren-9-yl (Pf) group.