30270-19-0Relevant academic research and scientific papers
New hybrid molecules with anticonvulsant and antinociceptive activity derived from 3-methyl- or 3,3-dimethyl-1-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]pyrrolidine-2,5-diones
Kamiński, Krzysztof,Zagaja, Miros?aw,Rapacz, Anna,?uszczki, Jarogniew J.,Andres-Mach, Marta,Abram, Micha?,Obniska, Jolanta
, p. 606 - 618 (2016)
The purpose of this study was to synthetize the focused library of 34 new piperazinamides of 3-methyl- and 3,3-dimethyl-(2,5-dioxopyrrolidin-1-yl)propanoic or butanoic acids as potential new hybrid anticonvulsants. These hybrid molecules join the chemical
Design, synthesis and anticonvulsant activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides
Kamiński, Krzysztof,Rapacz, Anna,Filipek, Barbara,Obniska, Jolanta
, p. 2938 - 2946 (2016)
The focused library of 21 new N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide, 2-(3-methyl-2,5-dioxopyrrolidin-1-yl)propanamide, and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives as potential new hybrid anticonvulsant agents was synthesized. These h
