30271-38-6

Basic information

• Product Name: 24-Hydroxycholesterol
• Synonyms: Cholest-5-ene-3,24-diol, (3β)-
• CAS NO: 30271-38-6
• Molecular Formula: C27H46O2
• Molecular Weight: 402.65294
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 30271-38-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 513.1±23.0 °C(Predicted)
• Appearance: /
• Density: 1.03±0.1 g/cm3(Predicted)
• PKA: 15.03±0.70(Predicted)
• CAS DataBase Reference: 24-Hydroxycholesterol(CAS DataBase Reference)
• NIST Chemistry Reference: 24-Hydroxycholesterol(30271-38-6)
• EPA Substance Registry System: 24-Hydroxycholesterol(30271-38-6)

Safety Data

• Hazardous Substances Data: 30271-38-6(Hazardous Substances Data)

Usage

Uses

24-Hydroxycholesterol is the main cholesterol elimination product of the brain and was found to be increased in serum of Alzheimer patients.

Upstream product

• 66461-41-4 6β-methoxy-3α,5-cyclocholestan-24-ol 
• 20905-62-8 24ξ-hydroxycholest-5-en-3β-yl acetate 
• 296758-98-0 24-hydroxycholesterol 3-(O)-tert-butyldimethylsilyl ether 
• 61947-94-2 cholesta-5,25-diene-3β,24ξ-diol 
• 17752-16-8 24-oxocholesterol 

Relevant articles and documents

Asymmetric Isopropylation of Steroidal 24-Aldehydes for the Synthesis of 24(R)-Hydroxycholesterol

The chiral β-amino alcohols-catalyzed addition of diisopropylzinc to steroidal 24-aldehydes successfully provided 24(R)-hydroxycholesterols in good yields with high diastereoselectivities, which are synthetic intermediates of 1α-24(R)-dihydroxyvitamin D3

Absolute configurations of 24 hydroxycholesterol and related compounds

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