3028-04-4

Basic information

• Product Name: Propanamide, N-2-benzothiazolyl-2-methyl- (9CI)
• Synonyms: Propanamide, N-2-benzothiazolyl-2-methyl- (9CI)
• CAS NO: 3028-04-4
• Molecular Formula: C11H12N2OS
• Molecular Weight: 220.29078
• Product Categories: BENZOTHIAZOLE
• Mol File: 3028-04-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanamide, N-2-benzothiazolyl-2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-2-benzothiazolyl-2-methyl- (9CI)(3028-04-4)
• EPA Substance Registry System: Propanamide, N-2-benzothiazolyl-2-methyl- (9CI)(3028-04-4)

Safety Data

• Hazardous Substances Data: 3028-04-4(Hazardous Substances Data)

Upstream product

• 79-30-1 isobutyryl chloride 
• 1141-88-4 2-Aminophenyl disulfide 
• 136-95-8 2-amino-benzthiazole 

Downstream Products

• 24622-32-0 N-isobutylbenzo[d]thiazole-2-amine 

Relevant articles and documents

Fragment-based design of selective GPCR ligands guided by free energy simulations

Fragment-based drug discovery relies on successful optimization of weakly binding ligands for affinity and selectivity. Herein, we explored strategies for structure-based evolution of fragments binding to a G protein-coupled receptor. Molecular dynamics s

Aerobic Copper-Mediated Domino Three-Component Approach to 2-Aminobenzothiazole Derivatives

An unprecedented three-component reaction involving a 2,2′-diaminodiaryl disulfide, copper cyanide, and an electrophile is described. This transformation is based on an oxidative copper-mediated S-cyanation as a key step and involves a cyanation/cyclization/acylation domino sequence enabling a rapid and efficient synthesis of diversely substituted 2-aminobenzothiazole derivatives. Notably, this reaction proceeds via an original mechanism involving an intermolecular migration of the acyl group.