302904-15-0Relevant articles and documents
4-Aryl-4H-Chromene-3-Carbonitrile Derivates: Synthesis and Preliminary Anti-Breast Cancer Studies
Thomas, Nancy,Zachariah, Subin Mary,Ramani, Prasanna
, p. 1778 - 1782 (2016)
A series of new 4-aryl-4H-chromene-3-carbonitrile derivatives were obtained by one-pot synthesis using substituted benzaldehydes, malononitrile, and substituted phenols. All the synthesized compounds (1a, 1b, 1c, 1d, 1e) were screened in vitro for antioxi
Prolinamide functionalized polyacrylonitrile fiber with tunable linker length and surface microenvironment as efficient catalyst for Knoevenagel condensation and related multicomponent tandem reactions
Zhu, Hai,Xu, Gang,Du, Huimin,Zhang, Chenlu,Ma, Ning,Zhang, Wenqin
, p. 217 - 229 (2019/05/16)
A series of new prolinamide polyacrylonitrile fiber catalysts with tunable length of alkyl linker and different linker group were prepared by covalent bonding for the first time and well characterized by mechanical strength, FT-IR, XRD, EA, TGA, SEM and water contact angel. The catalytic activities of these fiber catalysts were evaluated in Knoevenagel condensation and one-pot Knoevenagel-Michael multicomponent tandem reactions to synthesize α, β-unsaturated nitrile and 2-amino-4H-chromene derivatives in water. The result show that the suitable linker length attaching amines to fiber matrix as well as the constructed hydrophobic microenvironment by linker group within the surface layers of fiber materials effectively promotes the reactions. In addition, the good swollen capacity of fiber in solvent ensure that the reaction proceed well. Fiber catalyst PANPA?2F modified by prolinamide with a C2 alkyl chain exhibited the best catalytic performance and can be easily recovered and reused for at least ten consecutive cycles without significant loss of catalytic activity and active sites leaching.
Knoevenagel condensation shadowed by michael addition & o-alkylation of resorcinol, malononitrile and benzadehyde to form pyrrolidine, piperidine and morpholine substituted benzopyran derivatives in Dry K2CO3
Kulshrestha, Avidha,Pandey, Jaya,Panhekar, Deepa
, p. 1470 - 1472 (2019/06/11)
A condensation reaction of resorcinol, malononitrile and benzaldehyde in presence of sodium carbonate at room temperature on vigorous stirring gives 2-amino-7-hydroxy-4-phenyl-4H-1-benzopyran-3-carbonitrile which on alkylation in presence of dry potassium
Aqua-mediated multicomponent synthesis of various 4H-pyran derivatives catalyzed by poly(4-vinylpyridine)-supported copper iodide nanoparticle catalyst
Albadi, Jalal,Mansournezhad, Azam
, p. 5739 - 5752 (2016/06/01)
A green and efficient approach for synthesis of some new 4H-pyran derivatives is reported, catalyzed by green recyclable poly(4-vinylpyridine)-supported copper iodide nanoparticle catalyst in water. This procedure has many advantages such as operational s
Tungstic acid functionalized mesoporous SBA-15: A novel heterogeneous catalyst for facile one-pot synthesis of 2-amino-4H-chromenes in aqueous medium
Kundu, Sudipta K.,Mondal, John,Bhaumik, Asim
, p. 10515 - 10524 (2013/07/26)
A new highly ordered mesoporous tungstic acid functionalized SBA-15, TAFMC-1 has been synthesized via post-synthesis modification of mesoporous SBA-15 with (3-chloropropyl) triethoxysilane followed by substitution reaction of chlorine atom of the 3-chloropropyl group by tungstic acid group under refluxing conditions in n-hexane. The tungstic acid functionalized mesoporous silica material has been characterized by using small angle powder X-ray diffraction, N2 sorption, HR-TEM, FE-SEM, FT-IR and solid state MAS NMR studies. TAFMC-1 catalyzes the facile one-pot catalytic three-component condensation reaction of resorcinol, aromatic aldehyde and malononitrile for the synthesis of a diverse range of 2-amino-4H-chromenes in aqueous medium. This heterogeneous catalyst can be recycled very efficiently for six consecutive reaction cycles without significant loss of catalytic activity.
