303036-79-5Relevant academic research and scientific papers
Formation of (S)-5-cyclohexyl-5-phenyl-1,3-dioxolane-2,4-dione: A key intermediate in the synthesis of (S)-oxybutynin hydrochloride
Vandenbossche, Charles P.,De Croos, Philomen,Singh, Surendra P.,Bakale, Roger P.,Wagler, Thomas R.
, p. 921 - 925 (2011/03/20)
The synthesis of the drug candidate (S)-oxybutynin hydrochloride 1 is described. The procedure involves initial activation of (S)-cyclohexylmandelic acid 2, using isobutylchloroformate, followed by reaction of the resulting intermediate with 4-(diethylami
