303142-74-7

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 303142-78-1 β-(n-pentyl)methacryloyl chloride 
• 627-05-4 1-nitrobutane 
• 1383003-29-9 2-((benzyloxy)methyl)-2-methylcyclopent-4-ene-1,3-dione 
• 1383003-82-4 (2S,4R,5S)-2-(benzyloxy)methyl-4-((R)-1-hydroxybutyl)-2,5-dimethylcyclopentane-1,3-dione 
• 303142-80-5 (S)-3-((E)-(S)-2-Benzyloxymethyl-2-methyl-oct-3-enoyl)-4-isopropyl-oxazolidin-2-one 
• 303142-84-9 (R)-1-Benzyloxy-2-(2-ethyl-[1,3]dioxolan-2-yl)-2-methyl-octane-3,4-dione 
• 391612-32-1 (R)-1-Benzyloxy-2-(2-ethyl-[1,3]dioxolan-2-yl)-2-methyl-octane-3,4-diol 
• 303142-83-8 2-((E)-(S)-1-Benzyloxymethyl-1-methyl-hept-2-enyl)-2-ethyl-[1,3]dioxolane 
• 303142-82-7 (E)-(S)-4-Benzyloxymethyl-4-methyl-dec-5-en-3-one 
• 303142-86-1 (E)-(S)-4-Benzyloxymethyl-4-methyl-dec-5-en-3-ol 
• 303142-79-2 (S)-4-Isopropyl-3-((E)-2-methyl-oct-2-enoyl)-oxazolidin-2-one 
• 303142-81-6 (E)-(R)-2-Benzyloxymethyl-2-methyl-oct-3-en-1-ol 
• 302812-60-8 (E)-(S)-2-Benzyloxymethyl-2-methyl-oct-3-enal 

Downstream Products

• 1383003-85-7 (((1R,2S,3S)-2-(benzyloxy)methyl-4-butyl-2,5-dimethylcyclopent-4-ene-1,3-diyl)bis(oxy))bis(tert-butyldimethylsilane) 
• 1383003-84-6 (1R,2S,3S)-2-(benzyloxy)methyl-4-butyl-2,5-dimethylcyclopent-4-ene-1,3-diol 

Relevant academic research and scientific papers

Ag(I)-Catalyzed Kinetic Resolution of Cyclopentene-1,3-diones

An efficient kinetic resolution of readily available racemic cyclopentene-1,3-diones has been developed via a Ag(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides. This methodology shows good functional-group tolerance, delivering an array of synthetically valuable cyclopentene-1,3-diones with excellent stereoselectivity and generally high resolution efficiency (s = 48-226) accompanied by the biologically important fused pyrrolidine derivatives. Notably, this strategy allows facile access to the key intermediates for the synthesis of (+)-madindolines A and B.

Copper(I)-catalyzed asymmetric desymmetrization: Synthesis of five-membered-ring compounds containing all-carbon quaternary stereocenters

A highly stereoselective catalytic alkylation sequence for the synthesis of highly functionalized and versatile five-membered-ring compounds bearing all-carbon quaternary stereocenters was developed. Enantioselective desymmetrization of achiral cyclopentene-1,3-diones was thus executed by chiral Cu-phosphoramidite catalysts. A variety of complicated cyclopentane derivatives can be synthesized with excellent stereoselectivities using a low catalyst loading in a one-pot operation.

Novel stereoselective construction of a quaternary carbon: Application to synthesis of the cyclopentenedione moiety of madindolines

Enantioselective synthesis of the cyclopentenedione moiety of madindolines was achieved. Stereoselective construction of a quaternary carbon was realized by alkylation of an enolate possessing chiral auxiliary. Cyclopentenedione was derived from a triketone precursor by intramolecular condensation. (C) 2000 Elsevier Science Ltd.