303162-48-3

Usage

Functional Groups

Thiazole group (1,3-thiazol-5-yl)
Pyridine group (pyridin-2-yl)
Amine group (amine)

Versatility

The presence of thiazole, pyridine, and amine functional groups makes it a versatile molecule for drug design and discovery.

Biological Activities

Antimicrobial: Thiazole derivatives have been studied for antimicrobial activities.
Antifungal: Thiazole derivatives have shown potential antifungal properties.
Anticancer: Thiazole derivatives have been investigated for anticancer activities.

Chemical Structure

Unique combination of thiazole, pyridine, and amine groups.

Potential Applications

Pharmaceuticals: Can be used in drug discovery and development due to its versatile structure and potential biological activities.
Agrochemicals: May have applications in the development of agricultural chemicals due to the presence of functional groups commonly found in agrochemical compounds.

Building Blocks

Thiazole Derivatives: Thiazole compounds are often used as building blocks in drug discovery due to their diverse biological activities.
Pyridine Derivatives: Pyridine compounds serve as important building blocks in pharmaceuticals and agrochemicals.

Research and Development

Considered a valuable compound for further research and development in both pharmaceutical and agrochemical industries.

Upstream product

• 16536-94-0 pentanethioamide 

Relevant academic research and scientific papers

Substituted 1,3-thiazole compounds, their production and use

(1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.

JNK INHIBITOR

The present invention relates to a c-Jun N-terminal kinase inhibitor containing an azole compound (I) substituted by a nitrogen-containing aromatic group having substituent(s)(except a compound represented by the formula: ) or a salt thereof or a prodrug thereof.

5-PYRIDYL-1,3-AZOLE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF

An optionally N-oxidized compound represented by the formula: wherein R1 represents hydrogen, hydrocarbon, heterocycle, amino, acyl, R2 represents an aromatic group, R3 represents hydrogen, pyridyl, aromatic hydrocarbon, X represents oxygen, optionally oxidized sulfur, Y represents a bond, an oxygen, optionally oxidized sulfur, a group represented by the formula NR4 (R4 represents hydrogen, hydrocarbon or acyl) and Z represents a bond or a divalent acyclic hydrocarbon, or a salt thereof has an excellent adenosine A3 receptor antagonistic activity and is used as an agent for preventing or treating diseases related to an adenosine A3 receptor. Furthermore, the compound (I) or a salt thereof has p38 MAP kinase inhibitory activity and TNF-α inhibitory activity and is used as an agent for preventing or treating diseases related to p38 MAP kinase and diseases related to TNF-α.