303183-38-2Relevant academic research and scientific papers
Synthesis of model compounds for potential contrast agents containing phosphonate and peptide moieties
Shalem, Hutti,Shatzmiller, Shimon,Feit, Ben-Ami
, p. 2831 - 2837 (2007/10/03)
The synthesis of dimethyl 2-acetoxy-2-(2,4-diiodo-5-aminophenyl)ethylphosphonate and dimethyl 2-acetoxy-2-(2,4,6-triiodo-3,5-diaminophenyl)ethylphosphonate is described. Several amido and peptidic derivatives of these two compounds were prepared. These products are composed of a combination of structural/functional moieties which pave the way for their potential application as non-ionic selective X-ray contrast agents. The Royal Society of Chemistry 2000.
