30342-06-4

Basic information

• Product Name: (6R,6aR)-6,6a,11,14-Tetrahydro-8,9-dimethoxy-6-methyl-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine
• Synonyms: (+)-Thalictrifoline;(6R,6aR)-6,6a,11,14-Tetrahydro-8,9-dimethoxy-6-methyl-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine
• CAS NO: 30342-06-4
• Molecular Formula: C21H23NO4
• Molecular Weight: 353.41
• Mol File: 30342-06-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 155 °C
• Boiling Point: 463.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.30±0.1 g/cm3(Predicted)
• PKA: 6.57±0.40(Predicted)
• CAS DataBase Reference: (6R,6aR)-6,6a,11,14-Tetrahydro-8,9-dimethoxy-6-methyl-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,6aR)-6,6a,11,14-Tetrahydro-8,9-dimethoxy-6-methyl-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine(30342-06-4)
• EPA Substance Registry System: (6R,6aR)-6,6a,11,14-Tetrahydro-8,9-dimethoxy-6-methyl-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine(30342-06-4)

Safety Data

• Hazardous Substances Data: 30342-06-4(Hazardous Substances Data)

Upstream product

• 78986-98-8 (+/-)-trans-2,3-Dimethoxy-8-oxo-9,10-(methylenedioxy)-13-carboxytetrahydroprotoberberine 
• 75267-21-9 anhydride of 3,4-methylenedioxyhomophthalic acid 
• 3382-18-1 6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 79055-79-1 (+)-trans-2,3-Dimethoxy-8-oxo-9,10-(methylenedioxy)-13-(methoxycarbonyl)tetrahydroprotoberberine 
• 79055-77-9 (+)-trans-2,3-Dimethoxy-8-oxo-9,10-(methylenedioxy)-13-carboxytetrahydroprotoberberine 
• 79082-11-4 (+)-trans-2,3-Dimethoxy-8-oxo-9,10-(methylenedioxy)-13-(hydroxymethyl)tetrahydroprotoberberine 
• 79055-84-8 Methanesulfonic acid (6R,6aR)-8,9-dimethoxy-6,11,12,14-tetrahydro-6aH-[1,3]dioxolo[4,5-h]isoquino[2,1-b]isoquinolin-6-ylmethyl ester 

Relevant articles and documents

THE ABSOLUTE CONFIGURATIONS OF (+)-THALICTRIFOLINE AND (+)-CORYDALIC ACID METHYL ESTER. TOTAL SYNTHESIS OF (+)-THALICTRIFOLINE.

(+)-Thalictrifoline (3) has been synthesized from an optically resolved (+)-8-oxo-13-carboxytetrahydroprotoberberine (13) whose absolute configuration was established by correlation with (+)-18.This determines the absolute configurations of (+)-thalictrifoline (3) as 13R, 14R and (+)-corydalic acid methyl ester (9) as 3R, 4R.