30342-87-1

Basic information

• Product Name: 4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOLE-3-THIOL
• Synonyms: IFLAB-BB F0820-0346;ASISCHEM C56838;4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOLE-3-THIOL;4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOL-3-YL HYDROSULFIDE;AKOS TOT-0009;OTAVA-BB BB0109110026;3-Propyl-4-amino-4H-1,2,4-triazole-5-thiol;3-Propyl-4-amino-5-mercapto-4H-1,2,4-triazole
• CAS NO: 30342-87-1
• Molecular Formula: C₅H₁₀N₄S
• Molecular Weight: 158.22
• Mol File: 30342-87-1.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOLE-3-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOLE-3-THIOL(30342-87-1)
• EPA Substance Registry System: 4-AMINO-5-PROPYL-4H-1,2,4-TRIAZOLE-3-THIOL(30342-87-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 30342-87-1(Hazardous Substances Data)

Upstream product

• 105-54-4 butanoic acid ethyl ester 
• 2231-57-4 Thiocarbohydrazide 
• 107-92-6 butyric acid 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 139268-15-8 6-<5-(4-Chlorophenyl)-2-furyl>-3-propyl-1,2,4-triazolo<3,4-b>-1,3,4-thiadiazole 
• 623936-88-9 4-{[1-[5-(4-Methoxy-2-nitro-phenyl)-furan-2-yl]-meth-(E)-ylidene]-amino}-5-propyl-2,4-dihydro-[1,2,4]triazole-3-thione 
• 54025-95-5 3-propyl-6-(4-methylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 467243-72-7 C₁₄H₁₈N₄OS 
• 54025-83-1 3-propyl-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 54025-96-6 6-(4-nitro-phenyl)-3-propyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 

Relevant articles and documents

Synthesis and Biological Evaluation of 1,2,4-Triazole Thioethers as Both Potential Virulence Factor Inhibitors against Plant Bacterial Diseases and Agricultural Antiviral Agents against Tobacco Mosaic Virus Infections

Targeting the virulence factors of phytopathogenic bacteria is an innovative strategy for alleviating or eliminating the pathogenicity and rapid outbreak of plant microbial diseases. Therefore, several types of 1,2,4-triazole thioethers bearing an amide l

Synthesis and biological evaluation of some novel S-β-D-glucosides of 4-amino-5-alkyl-1,2,4-triazole-3-thiones derivatives

A novel series of 3-S-β-D-glucosides-4-arylideneamino-5-alkyl-1,2,4-triazoles were designed and synthesized by reaction of 4-amino-5-alkyl-4H-1,2,4triazole-3-thiol Schiff bases and 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide. The structures of the target compounds have been characterized by 1H NMR, 13C NMR, FT-IR, and Microanalyses. All the newly synthesized compounds have been screened for their in vitro antibacterial and antifungal activities against two Gram-positive bacteria [Bacillus cereus (PTCC 1015) and Staphylococcus aureus (ATCC 25923)], two Gram-negative bacteria [Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (PTCC 1399) and two fungi [Aspergillus Niger (PTCC 5012) and Candida albicans (PTCC 5027)].

Design, Synthesis and Evaluation of Antitubercular Activity of Novel 1,2,4-Triazoles Against MDR Strain of Mycobacterium tuberculosis

Emergence of various forms of resistant strains of Mycobacterium tuberculosis led to the exploration of drugs with novel mechanism of action. Recently econazole, an azole based antitubercular agent, attracted major attention for targeting mycobacterial cytochrome P450. In the present study, we designed novel 1,2,4-triazole derivatives based on econazole moiety and evaluated them for in vitro antitubercular activity against M. tuberculosis H37Rv and multi-drug resistant (MDR) strains of Mycobacterium.