30362-03-9Relevant academic research and scientific papers
Hydration with mercuric acetate and the reduction with 9-BBN-H of 2-(1-alkenyl)-4,6-dimethyl-s-triazines
Nyquist, H. LeRoy,Beeloo, Edward A.,Hurlbut, Lydia S.,Watson-Clark, Rachel,Harwell, David E.
, p. 3202 - 3212 (2007/10/03)
Oxymercuration-demercuration of a double bond in conjugation with the 4,6-dimethyl-s-triazin-2-yl substituent as in alkenes la,b gave anti-Markovnikov regioselectivity, which is explained by the electron-withdrawing nature of the triazinyl substituent. However, hydroboration of the conjugated alkenes with 9-BBN-H gave the corresponding alkenes 5a-c under normal workup conditions with or without oxidation. With time and without workup the hydroboration of 1b gave spectral evidence for the formation of intermediates 9-13 resulting from the migration of the 9-BBN moiety from the α-carbon to a ring nitrogen with concurrent formation of an exocyclic double bond to an α-carbon of the ring. Hydrolysis of the intermediates gave 5a-c. A possible mechanism involving successive allylic rearrangements is presented.
