303727-84-6Relevant articles and documents
High 1,5-anti stereoinduction in boron-mediated aldol reactions of methyl ketones
Dias, Luiz C.,Bau, Rosana Z.,De Sousa, Marcio A.,Zukerman-Schpector
, p. 4325 - 4327 (2002)
(equationpresented) We report herein a very efficient and synthetically useful 1,4-anti-1,5-anti boron-mediated aldol reaction of a chiral α-methyl-β-alkoxy methyl ketone with achiral aldehydes. * Fax: +55-019-3788-3023. ? This paper is dedicated to the B
Gram-scale synthesis of (+)-discodermolide.
Smith 3rd.,Kaufman,Beauchamp,LaMarche,Arimoto
, p. 1823 - 1826 (2008/02/11)
[formula: see text] A triply convergent, highly efficient second-generation synthesis of the potent antimitotic agent (+)-discodermolide (1) has been achieved on a 1-g scale.