30379-58-9Relevant articles and documents
Preparation process of methyl glycolate
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Paragraph 0029-0055, (2021/11/03)
The preparation process comprises the following steps: firstly adding an organic solvent and glycolic acid into a three-necked flask, stirring at low temperature, adding bromide, and controlling the reaction temperature to be low temperature. The reaction
METHOD FOR PREPARING ALKYL HYDROXYL ACID ESTER AND USE THEREOF
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Page/Page column 6, (2021/09/17)
Provided is a method for preparing an alkyl hydroxyl acid ester, the product and use thereof. The method has advantages of high yield, not producing waste water, gas, or solid, low cost, and is green and environment friendly.
Fluorinated taxane compound, preparation method therefor and application of fluorinated taxane compound
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Paragraph 0048-0054, (2019/08/30)
The invention discloses a fluorinated taxane compound, a preparation method therefor and an application of the fluorinated taxane compound. The compound has a structural general formula represented bya formula I. Proven by pharmacological experiments, compared with paclitaxel, a series of fluorinated taxane derivatives synthesized by the method have cytotoxicity superior to that of the paclitaxelto a multidrug-resistant human mammary cancer cell line MCF-7/Adr and an ovarian cancer cell line NCI/Adr and represent cytotoxicity superior to that of the paclitaxel to a colon cancer cell line HCT-116 with overexpressed neoplasm stem cells.