304015-63-2

Upstream product

• 304015-61-0 N,N-bis(2-{[tert-butyldimethylsilyl]oxy}ethyl)-4-nitroaniline 
• 39070-14-9 1-methyl-2-nitro-5-hydroxymethylimidazole 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 18226-17-0 N,N-bis(2-hydroxyethyl)-4-nitroaniline 
• 246536-87-8 (1-methyl-2-nitro-1H-imidazol-5-yl)methyl (4-nitrophenyl) carbonate 
• 304015-62-1 N,N-bis(2-{[tert-butyldimethylsilyl]oxy}ethyl)-1,4-benzenediamine 

Downstream Products

• 304015-64-3 (1-methyl-2-nitro-1H-imidazol-5-yl)methyl 4-[bis(2-hydroxyethyl)amino]phenylcarbamate 

Relevant academic research and scientific papers

Synthesis and Evaluation of Nitroheterocyclic Carbamate Prodrugs for Use with Nitroreductase-Mediated Gene-Directed Enzyme Prodrug Therapy

A variety of nitroheterocyclic carbamate prodrugs of phenylenediamine mustard and 5-amino-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbonyl]-1, 2-dihydro-3H-benz[e]indoline (aminoseco-CBI-TMI), covering a wide range of reduction potential, were pre