30415-02-2

Upstream product

• 106089-51-4 4-chloro-3-(1-chlorovinyl)-6-methyl-2-pyrone 
• 95-54-5 1,2-diamino-benzene 
• 126292-61-3 4-chloro-3-ethynyl-6-methyl-2H-pyran-2-one 
• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 
• 151537-03-0 3,11-Dimethyl-5H-2-oxa-5,10-diaza-dibenzo[a,d]cyclohepten-1-one 

Relevant academic research and scientific papers

Synthesis of 6-, 7-, 8- or 9-substituted 1H-pyrano[4,3-b]-quinoline derivatives by the cyclization of 3 -acetyl-4-arylamino-2H-pyran-2-one derivatives

Heating of 3-acetyl-4-arylamino-6-methyl-2H-pyran-2-one derivatives in coned HaSO4 gave 6-, 7-, 8- or 9-substituted 3,10-dimethyl-1H-pyrano[4,3-b]quinoline derivatives.

SYNTHESES OF PYRANOBENZODIAZEPINE AND PYRANOQUINOLINE USING 4-CHLORO-3-(1-CHLOROVINYL)-6-METHYL-2H-PYRAN-2-ONE AND 4-CHLORO-3-ETHYNYL-6-METHYL-2H-PYRAN-2-ONE

Reaction of dichloropyrone (1) and chloroethynylpyrone (2) with o-phenylenediamine and m-phenylenediamine give pyranobenzodiazepine (3) and pyranoquinoline (5), respectively.Treatment 1 and 2 with p-phenylenediamine yield aminoethynylpyrone (6), which is a key product in the reaction of 1 and 2 with phenylenediamines.