304457-04-3

Upstream product

• 70-11-1 α-bromoacetophenone 
• 345641-34-1 2-acetamido-2,5,5-trimethyl-1,3-dioxane 
• 6414-07-9 (2,5,5-Trimethyl-[1,3]dioxan-2-yl)-acetic acid methyl ester 

Downstream Products

• 345641-49-8 (5R,9S)-9-Acetoxy-5-[(S)-2-furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-6-oxo-3-(2-oxo-propyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 
• 345641-52-3 3-[4-[1-(tert-butyl-dimethyl-silanyloxy)-3-(2-nitro-phenylselanyl)-propyl]-2-(2,5,5-trimethyl-[1,3]dioxan-2-ylmethyl)-furan-3-yl]-propionitrile 
• 345641-48-7 (5R,9S)-5-[(S)-2-Furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-9-hydroxy-6-oxo-3-(2-oxo-propyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 
• 304457-21-4 9-(tert-butyl-dimethyl-silanyloxy)-5-[2-furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-6-oxo-3-(2,5,5-trimethyl-[1,3]dioxan-2-ylmethyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 
• 304457-16-7 9-(tert-butyl-dimethyl-silanyloxy)-5-[2-furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-6-oxo-3-(2,5,5-trimethyl-[1,3]dioxan-2-ylmethyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 
• 304457-18-9 (5S,9S)-9-Acetoxy-5-[(S)-2-furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-6-oxo-3-(2-oxo-propyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 
• 304457-17-8 (5S,9S)-5-[(S)-2-Furan-3-yl-2-(4-methoxy-benzyloxy)-ethyl]-9-hydroxy-6-oxo-3-(2-oxo-propyl)-4,5,6,7,8,9-hexahydro-cycloocta[c]furan-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A regioselective route to 2,3,4-trisubstituted furans

Several potential routes to furans substituted with C-C bonds at the 2-,3-, and 4- positions have been evaluated.

Teubrevin G and teubrevin H: The first total syntheses of rearranged neo-clerodanes including solutions to the problems of chirality merger and furan ring assembly

Total syntheses of teubrevins G (2) and H (3) are described. The reported strategy relies on a highly regioselective cycloaddition-fragmentation approach to the construction of a 2,3,4-trisubstituted furan and features efficient ring-closing metathesis ch