304458-32-0Relevant academic research and scientific papers
meta-Selective C?H Borylation of Benzylamine-, Phenethylamine-, and Phenylpropylamine-Derived Amides Enabled by a Single Anionic Ligand
Davis, Holly J.,Genov, Georgi R.,Phipps, Robert J.
supporting information, p. 13351 - 13355 (2017/10/07)
Selective functionalization at the meta position of arenes remains a significant challenge. In this work, we demonstrate that a single anionic bipyridine ligand bearing a remote sulfonate group enables selective iridium-catalyzed borylation of a range of common amine-containing aromatic molecules at the arene meta position. We propose that this selectivity is the result of a key hydrogen bonding interaction between the substrate and catalyst. The scope of this meta-selective borylation is demonstrated on amides derived from benzylamines, phenethylamines and phenylpropylamines; amine-containing building blocks of great utility in many applications.
Preparation of photoactivable amino acid derivatives
Debieux, Jean-Luc,Bochet, Christian G.
experimental part, p. 4519 - 4524 (2009/10/17)
(Chemical Equation Presented) A range of N-protected-R-amino acyl-5,7-dinitroindolines 3a-z were prepared in good yields from commercially available N-protected-R-amino acids 1a-z by a two-step sequence of acylation and intramolecular amide N-arylation. S
