30448-32-9

Basic information

• Product Name: Propanoic acid, 2-methyl-3-(phenylamino)-, methyl ester
• CAS NO: 30448-32-9
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Mol File: 30448-32-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-3-(phenylamino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-3-(phenylamino)-, methyl ester(30448-32-9)
• EPA Substance Registry System: Propanoic acid, 2-methyl-3-(phenylamino)-, methyl ester(30448-32-9)

Safety Data

• Hazardous Substances Data: 30448-32-9(Hazardous Substances Data)

Upstream product

• 80-62-6 methacrylic acid methyl ester 
• 62-53-3 aniline 
• 20609-71-6 3-bromo-2-methyl-propionic acid methyl ester 

Relevant articles and documents

Benefits of a Dual Chemical and Physical Activation: Direct aza-Michael Addition of Anilines Promoted by Solvent Effect under High Pressure

The unique combination of hexafluoroisopropanol (HFIP) employed as solvent and hyperbaric conditions (10-15 kbar) allows unprecedented 1,4-addition of poor nucleophiles, such as aromatic amines, onto sluggish (cumbersome) Michael acceptors without any promoter or workup.

Silicon tetrachloride catalyzed aza-michael addition of amines to conjugated alkenes under solvent-free conditions

The efficient and very simple conjugate addition of aromatic and aliphatic amines to α,β-unsaturated carbonyl compounds under solvent-free conditions in the presence of catalytic amount of silicon tetrachloride is reported. The reaction of aryl and alkyl amines with different Michael acceptors gave the corresponding Michael adducts with simple catalyst and good to excellent yields. Georg Thieme Verlag Stuttgart New York.