30461-24-6

Upstream product

• 313647-36-8 2-phenyl-3a,4,6,6a-tetrahydrothieno<3,4-d>oxazole 
• 30452-80-3 trans-4-benzoylamino-3-hydroxythiophane 
• 93-97-0 benzoic acid anhydride 
• 30461-27-9 2-amino-2,3-dideoxy-4-thio-DL-glycero-tetrofuranose hydrochloride 

Downstream Products

• 313647-36-8 2-phenyl-3a,4,6,6a-tetrahydrothieno<3,4-d>oxazole 
• 30452-80-3 cis-4-benzoylamino-3-hydroxythiophane 

Relevant academic research and scientific papers

Thio-sugars. Part 10. The Nucleoside from 5-Fluoroacil and 2-Amino-2,3-dideoxy-4-thio-DL-glycero-tetrofuranose and Related Compounds

Another molecular combination of a chloroethylnitrosourea and a pyrimidine antimetabolite (5-fluorouracil) linked through a sugar or sugar-like moiety has been synthesised for biological testing.In this case 2-amino-2,3-dideoxy-4-thio-DL-glycero-tetrofuranose was derived from thiolan-3-one, nitrogen being introduced as azide in preference to the route involving oxime and phthalimide.Some derivatives of 3-amino-3-deoxy-4-thio-DL-erythrofuranose were prepared from trans-4-aminothiolan-3-ol, inverted by way of a fused oxazoline, but although a (5-iodouracil) nucleoside ester was obtained it proved difficult to remove the protecting groups.