304658-76-2Relevant academic research and scientific papers
Identification of Prime Factors to Maximize the Photocatalytic Hydrogen Evolution of Covalent Organic Frameworks
Abe, Ryu,Baburin, Igor,Ghosh, Samrat,Heine, Thomas,Kaji, Hironori,Kawaguchi, Takahiro,Kuc, Agnieszka,Nakada, Akinobu,Seki, Shu,Springer, Maximilian A.,Suzuki, Hajime,Suzuki, Katsuaki
supporting information, p. 9752 - 9762 (2020/07/25)
Visible-light-driven hydrogen (H2) production from water is a promising strategy to convert and store solar energy as chemical energy. Covalent organic frameworks (COFs) are front runners among different classes of organic photocatalysts. The photocatalytic activity of COFs depends on numerous factors such as the electronic band gap, crystallinity, surface area, exciton migration, stability of transient species, charge separation and transport, etc. However, it is challenging to fine tune all of these factors simultaneously to enhance the photocatalytic activity. Hence, in this report, an effort has been made to understand the interplay of these factors and identify the key factors for efficient photocatalytic H2 production through a structure-property-activity relationship. Careful molecular engineering allowed us to optimize all of the above plausible factors impacting the overall catalytic activities of a series of isoreticular COFs. The present study determines three prime factors: light absorption, charge carrier generation, and its transport, which influence the photocatalytic H2 production of COFs to a much greater extent than the other factors.
BIO-ORTHOGONAL DRUG ACTIVATION
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Paragraph 0212, (2016/05/19)
The invention relates to a Prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention also relates to a Prodrug kit comprising at least one Prodrug and at least one Activator, wherein the Prodrug comprises a Drug and a first Bio-orthogonal Reactive Group (the Trigger), and wherein the Activator comprises a second Bio-orthogonal Reactive Group. The invention also relates to targeted therapeutics used in the above-mentioned method and kit. The invention particularly pertains to antibody-drug conjugates and to bi- and trispecific antibody derivatives.
Practical synthesis of bis-substituted tetrazines with two pendant 2-pyrrolyl or 2-thienyl groups, precursors of new conjugated polymers
So?oducho, Jadwiga,Doskocz, Jacek,Cabaj, Joanna,Roszak, Szczepan
, p. 4761 - 4766 (2007/10/03)
Novel linear oligoheterocycles based on substituted tetrazines are described. The desired compounds have been accomplished by a variation of the original Pinner [Ann. Chem., 297 (1897) 221] synthesis in which the aromatic nitrile reacted with hydrazine in
