304660-52-4Relevant academic research and scientific papers
Palladium-catalyzed reactions of N-allylbenzotriazoles with amines: Intramolecular allylamination routes to 2-vinylpyrrolidines and 2- vinylpiperidines
Katritzky, Alan R.,Yao, Jiangchao,Yang, Baozhen
, p. 6066 - 6070 (1999)
Reactions of allylbenzotriazole (4a-d) with 1-bromo-3-chloropropane, 1- bromo-2-methyl-3-chloropropane, epibromohydrin (8), and 1-bromo-4- chlorobutane afforded the corresponding α-substituted allylbenzotriazoles (5a-d, 9, and 16a,b), which with primary amines in one-pot sequences produce 2-vinylpyrrolidines (7a-i), 2-ethylpyrrole (13), and 2-vinylpiperidines (18a- c) in good yields under mild conditions.
