304664-16-2

Upstream product

• 79-30-1 isobutyryl chloride 
• 6315-89-5 3,4-dimethoxyaniline 
• 18362-64-6 2,6-dimethyl-3,5-heptanedione 

Downstream Products

• 1416236-31-1 N-(2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-4,5-dimethoxyphenyl)isobutyramide 
• 1222482-66-7 C₂₃H₃₅NO₅ 
• 1222482-65-6 C₂₃H₃₅NO₅ 
• 649763-35-9 6-[(3,4-dimethoxy-phenyl)-isobutyl-amino]-1H-pyrimidine-2,4-dione 
• 649763-34-8 3,4-dimethoxy-N-isobutylaniline 

Relevant academic research and scientific papers

AIBN-promoted amidation of anilines with 1, 3-diketones via oxidative cleavage of C–C bond under aerobic conditions

N-Acylation of anilines with 1, 3-diketones promoted by AIBN (2-2′-azoisobutyronitrile) under metal-free and peroxide-free conditions in the presence of molecular oxygen as oxidant has been described. This protocol proceeds by the oxidative cleavage of C–C bond with simultaneous intermolecular C–N bond formation under mild conditions.

Model Systems for Flavoenzyme Activity: Relationships between Cofactor Structure, Binding and Redox Properties

A series of flavins were synthesized bearing electron-withdrawing and -donating substituents. The electrochemical properties of these flavins in a nonpolar solvent were determined. The recognition of these flavins by a diamidopyridine (DAP) receptor and the effect this receptor has on flavin redox potential was also quantified. It was found that the DAP-flavin binding affinity and the reduction potentials (E1/2) for both the DAP-bound and unbound flavins correlated well with functions derived from linear free energy relationships (LFERs). These results provide insight and predictive capability for the interplay of electronics and redox state-specific interactions for both abiotic and enzymatic systems.