30470-32-7Relevant academic research and scientific papers
An efficient palladium-catalyzed route to N-allylanilines by the direct use of allyl alcohols
Yang, Shyh-Chyun,Hung, Chung-Wei
, p. 1747 - 1752 (1999)
The direct activation of C-O bonds in allyl alcohols by palladium complexes has been accelerated by carrying out the reactions in the presence of titanium(IV) isopropoxide and molecular sieves (4A). N-Allylation of anilines to give mono- and diallylanilines directly using allyl alcohols has been realized by employing palladium catalysts.
Aqueous-mediated N-alkylation of amines
Singh, Chingakham B.,Kavala, Veerababurao,Samal, Akshaya K.,Patel, Bhisma K.
, p. 1369 - 1377 (2008/09/17)
Direct N-alkylation of primary amines to secondary/tertiary amines and of secondary amines to tertiary amines has been achieved in excellent yields by employing alkyl, benzylic and allylic halides in the presence of NaHCO 3 in an aqueous medium at an elevated temperature. Amines of different stereoelectronic nature react with ease with different halides. The selective formation of secondary amines and the formation of three different substituted tertiary amines are some of the interesting features of this methodology. Reaction in an aqueous medium, operationally convenient conditions, excellent yields and innocuous byproducts, and the absence of transition-metal catalysts, expensive bases, solid supports and the formation of undesired quaternary ammonium salts makes this method a green chemical process. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Palladium-catalyzed N-allylation of anilines by direct use of allyl alcohols in the presence of titanium(IV) isopropoxide
Yang, Shyh-Chyun,Chung, Wen-Hung
, p. 953 - 956 (2007/10/03)
The direct activation of C-O bonds in allyl alcohols by palladium complexes has been accelerated by carrying out the reactions in the presence of titanium(IV) isopropoxide and 4A molecular sieves. N-Allylation of anilines to give mono- and diallylanilines using allyl alcohols directly has been realized by employing palladium catalysts.
