p-Tosyl-methyl magnesium bromide, also known as p-toluenesulfonylmethylmagnesium bromide, is an organomagnesium compound with the chemical formula C8H9BrMgOS. It is a colorless to pale yellow liquid that is highly sensitive to air and moisture. This reagent is commonly used in organic synthesis, particularly in the formation of carbon-carbon bonds through the addition of Grignard reagents to aldehydes and ketones. The p-toluenesulfonyl (Ts) group serves as a protecting group for the carbonyl functionality, which can be later removed under mild acidic conditions. The compound is prepared by reacting p-toluenesulfonylmethyl chloride with magnesium in the presence of a suitable solvent, such as diethyl ether or tetrahydrofuran. Due to its reactivity, p-tosyl-methyl magnesium bromide is typically used in situ and requires careful handling under an inert atmosphere.
3048-28-0
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Basic information
- Product Name: p-tosyl-methyl magnesium bromide
- Synonyms:
- CAS NO:3048-28-0
- Molecular Formula:
- Molecular Weight: 273.433
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: p-tosyl-methyl magnesium bromide(CAS DataBase Reference)
- NIST Chemistry Reference: p-tosyl-methyl magnesium bromide(3048-28-0)
- EPA Substance Registry System: p-tosyl-methyl magnesium bromide(3048-28-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3048-28-0(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3048-28-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,4 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.Calculate Digit Verification of CAS Registry Number 3048-28:
(6*3)+(5*0)+(4*4)+(3*8)+(2*2)+(1*8)=70
70 % 10 = 0
So 3048-28-0 is a valid CAS Registry Number.
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p-tosyl-methyl magnesium bromide
