304857-39-4

Basic information

• Product Name: 6,8-Methanoquinoline, 2-chloro-5,6,7,8-tetrahydro-7,7-dimethyl-, (6R,8R)-
• CAS NO: 304857-39-4
• Molecular Formula: C12H14ClN
• Molecular Weight: 207.703
• Mol File: 304857-39-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6,8-Methanoquinoline, 2-chloro-5,6,7,8-tetrahydro-7,7-dimethyl-, (6R,8R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-Methanoquinoline, 2-chloro-5,6,7,8-tetrahydro-7,7-dimethyl-, (6R,8R)-(304857-39-4)
• EPA Substance Registry System: 6,8-Methanoquinoline, 2-chloro-5,6,7,8-tetrahydro-7,7-dimethyl-, (6R,8R)-(304857-39-4)

Safety Data

• Hazardous Substances Data: 304857-39-4(Hazardous Substances Data)

Upstream product

• 38651-65-9 (1R,5S)-(+)-nopinone 

Downstream Products

• 819084-07-6 (6R,6'R,8R,8'R)-(+)-benzyl-bis(5,6,7,8-tetrahydro-7,7-dimethyl-6,8-methanoquinolin-2-yl)-amine 

Relevant articles and documents

New Lewis-Basic N-Oxides as Chiral Organocatalysts in Asymmetric Allylation of Aldehydes

Allylation of aromatic and heteroaromatic aldehydes 1a-k with allyltrichlorosilane 2 can be catalyzed by the new heterobidentate, terpene-derived bipyridine N-monoxides 4, 6a,b, and 8-11 (≤10 mol %) to afford (S)-(-)-3 with high enantioselectivities (≤99% ee). The stereochemical outcome has been found to be controlled by the axial chirality of the catalyst, which in turn is determined by the central chirality of the annulated terpene units. Solvent effects on the conversion and the level of asymmetric induction have been elucidated, and MeCN has been identified as the optimal solvent for these catalysts.