304863-09-0Relevant articles and documents
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice
Frydman, Benjamin,Blokhin, Andrei V.,Brummel, Sara,Wilding, George,Maxuitenko, Yulia,Sarkar, Aparajita,Bhattacharya, Subhra,Church, Dawn,Reddy, Venodhar K.,Kink, John A.,Marton, Laurence J.,Valasinas, Aldonia,Basu, Hirak S.
, p. 4586 - 4600 (2003)
Polyamine analogues 7, 10, 18, 27, and 32 containing cyclopropane rings were obtained by chemical synthesis. Their antineoplastic activities were assessed against the cultured human prostate tumor cell lines DU-145, DuPro, and PC-3. Decamines 32 and 27 ex