304884-75-1

Basic information

• Product Name: N-(2,6-dichlorophenyl)phenylacetamide
• CAS NO: 304884-75-1
• Molecular Weight: 280.153
• Mol File: 304884-75-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,6-dichlorophenyl)phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-dichlorophenyl)phenylacetamide(304884-75-1)
• EPA Substance Registry System: N-(2,6-dichlorophenyl)phenylacetamide(304884-75-1)

Safety Data

• Hazardous Substances Data: 304884-75-1(Hazardous Substances Data)

Upstream product

• 103-80-0 phenylacetyl chloride 
• 608-31-1 2,6-Dichloroaniline 

Downstream Products

• 15307-79-6 diclofenac sodium 
• 15362-40-0 1-(2,6-dichlorophenyl)indolin-2-one 

Relevant articles and documents

1 - Aryl -2 - indolinone derivatives preparation method

The invention discloses a method for synthesis of 1-aryl-2-indolinone derivatives. The method comprises the following steps: dissolving N-aryl-substituted phenylacetamide (III) in an organic solvent, adding a chlorination reagent and carrying out a reaction so as to obtain N-chloro-N-aryl-substituted phenylacetamid (II); and subjecting N-chloro-N-aryl-substituted phenylacetamid to a reaction with a certain amount of Lewis acid and a proper amount of an organic solvent at a certain temperature so as to obtain 1-aryl-2-indolinone (I). The method provided by the invention has the advantages of simple operation, easily available reagents, a low price, mild conditions and capability of synthesizing a plurality of 1-aryl-2-indolinone (I) compounds.