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Angiotensin I converting enzyme 2 (ACE-2) substrate is a pivotal chemical within the renin-angiotensin system, responsible for the conversion of angiotensin I to angiotensin 1-9 and angiotensin II to angiotensin 1-7. These conversions result in vasodilation and anti-inflammatory effects, which are essential for maintaining cardiovascular health by counteracting the vasoconstrictive and pro-inflammatory impacts of the angiotensin converting enzyme (ACE) pathway. Furthermore, ACE-2 serves as the entry receptor for the SARS-CoV-2 virus, highlighting its significance in research and drug development, particularly in the context of the COVID-19 pandemic.

305336-82-7

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305336-82-7 Usage

Uses

Used in Pharmaceutical Research and Development:
ACE-2 substrate is utilized as a target for drug development to combat the SARS-CoV-2 virus, which is responsible for the COVID-19 pandemic. By modulating the activity of ACE-2, researchers aim to develop therapeutics that can either inhibit viral entry or leverage the enzyme's protective effects to mitigate the severity of the disease.
Used in Cardiovascular Health Applications:
In the context of cardiovascular health, ACE-2 substrate is employed as a therapeutic agent to promote vasodilation and reduce inflammation. This helps in managing conditions such as hypertension, where the regulation of blood pressure is crucial. The activation of ACE-2 can counteract the effects of the ACE pathway, thus contributing to the overall cardiovascular well-being.
Used in Biochemical and Physiological Studies:
ACE-2 substrate is also used as a research tool in biochemical and physiological studies to understand the intricate mechanisms of the renin-angiotensin system. This knowledge aids in uncovering the complex interplay between different components of the system and their impact on various physiological processes, including blood pressure regulation and immune response.
Used in Diagnostics:
ACE-2 substrate can be employed in diagnostic assays to assess the activity or expression levels of ACE-2 in biological samples. This can be particularly useful in monitoring the progression of diseases that involve the renin-angiotensin system, such as hypertension and cardiovascular diseases, as well as in evaluating the effectiveness of therapeutic interventions targeting the enzyme.
Used in Nutritional and Health Supplements:
Given its role in cardiovascular health and inflammation regulation, ACE-2 substrate may also be incorporated into nutritional supplements or health products. These supplements could potentially support individuals in maintaining a healthy blood pressure and reducing inflammation, contributing to overall well-being and disease prevention.

Check Digit Verification of cas no

The CAS Registry Mumber 305336-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,3,3 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 305336-82:
(8*3)+(7*0)+(6*5)+(5*3)+(4*3)+(3*6)+(2*8)+(1*2)=117
117 % 10 = 7
So 305336-82-7 is a valid CAS Registry Number.

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