30540-18-2Relevant academic research and scientific papers
Pyrimidine Derivatives and Related Compounds. Part 42. Isolation of the Intermediates in the Ring Transformation of 1,3-Oxazine-2,4-diones into Pyrimidines and Pyrasoles, and their Structure Determination by 15N Nuclear Magnetic Resonance Analysis
Yogo, Motoi,Hirota, Kosaku,Senda,Shigeo
, p. 473 - 475 (1982)
Reaction of the 6-methyl-1,3-oxazine-2,4-diones (1) and (2) with hydrazine hydrate at room temperature gave the 6-hydroxy-5,6-dihydrouracils (7a) and (8a).The structures of the products were determined by 15N n.m.r. analysis.The mechanism of the ring transformation of 1,3-oxazines into pyrimidines and pyrazoles is discussed.
