30564-98-8 Usage
Uses
Used in Chemical Research:
3,3-Dimethylbutan-1-amine hydrochloride is used as a chemical intermediate for the synthesis of various organic compounds. Its amine group can participate in a range of reactions, such as alkylation, acylation, and reductive amination, making it a versatile building block in organic chemistry.
Used in Coordination Chemistry:
3,3-Dimethylbutan-1-amine hydrochloride is used as a ligand in coordination chemistry to study the coordination tendencies of N-substituted iminoacetic acids. The amine group in 3,3-dimethylbutan-1-amine hydrochloride can form coordination complexes with metal ions, providing insights into the structure and properties of such complexes.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 3,3-dimethylbutan-1-amine hydrochloride could potentially be used in the pharmaceutical industry as a starting material for the synthesis of various drug candidates. Its amine functionality and structural features may be exploited to design novel bioactive molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 30564-98-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,5,6 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 30564-98:
(7*3)+(6*0)+(5*5)+(4*6)+(3*4)+(2*9)+(1*8)=108
108 % 10 = 8
So 30564-98-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H15N.ClH/c1-6(2,3)4-5-7;/h4-5,7H2,1-3H3;1H
30564-98-8Relevant academic research and scientific papers
Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3- d ]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells
Henry, James R.,Kaufman, Michael D.,Peng, Sheng-Bin,Ahn, Yu Mi,Caldwell, Timothy M.,Vogeti, Lakshminarayana,Telikepalli, Hanumaiah,Lu, Wei-Ping,Hood, Molly M.,Rutkoski, Thomas J.,Smith, Bryan D.,Vogeti, Subha,Miller, David,Wise, Scott C.,Chun, Lawrence,Zhang, Xiaoyi,Zhang, Youyan,Kays, Lisa,Hipskind, Philip A.,Wrobleski, Aaron D.,Lobb, Karen L.,Clay, Julia M.,Cohen, Jeffrey D.,Walgren, Jennie L.,McCann, Denis,Patel, Phenil,Clawson, David K.,Guo, Sherry,Manglicmot, Danalyn,Groshong, Chris,Logan, Cheyenne,Starling, James J.,Flynn, Daniel L.
, p. 4165 - 4179 (2015/06/08)
The RAS-RAF-MEK-MAPK cascade is an essential signaling pathway, with activation typically mediated through cell surface receptors. The kinase inhibitors vemurafenib and dabrafenib, which target oncogenic BRAF V600E, have shown significant clinical efficac
2-AMINO, 6-PHENYL SUBSTITUTED PYRIDO [2, 3 - D] PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS
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Page/Page column 13-14, (2013/09/26)
The present invention provides the compound l-(3,3-Dimethylbutyl) -3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea or a pharmaceutically acceptable salt thereof, that inhibits Raf and, therefore, may be useful in tr
