30578-37-1 Usage
Originator
Regulton,Nordmark,W. Germany,1981
Manufacturing Process
18.7 parts of 1-phenyl-4-aminopyridazone-(6) and 19 parts of dimethyl
sulfate in 400 parts of xylene are kept at 120°C for one hour while mixing
well. The reaction mixture is suction filtered, 28 parts (89.5% of the theory)
of 1-phenyl-4-amino-6-methoxypyridazinium methosulfate is obtained having
a melting point of 173°C to 174°C after recrystallization from acetonitrile. The
perchlorate has a melting point of 179°C to 182°C.
Check Digit Verification of cas no
The CAS Registry Mumber 30578-37-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,5,7 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 30578-37:
(7*3)+(6*0)+(5*5)+(4*7)+(3*8)+(2*3)+(1*7)=111
111 % 10 = 1
So 30578-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4)
30578-37-1Relevant articles and documents
Amezinium. Synthesis and radioactive labelling
Reicheneder,Burger,Koenig,Kropp,Lietz,Thyes,Wiersdorff
, p. 1529 - 1533 (2007/10/02)
The synthesis of the novel pharmacologically active substance 4-amino-6-methoxy-1-phenyl-pyridazinium methyl sulfate (ameziniummetilsulfate, LU 1631, Regulton) and the proof of its structure are described. In addition the present paper deals with the microsynthesis of samples which are labelled at a definite site with 14C or 3H, respectively, and which are needed for the examination of its metabolism and the pharmacokinetics.
