305800-04-8

Basic information

• Product Name: 6-(3-Benzoyl-phenyl)4,4-dimethyl-1,4-dihydro-benzo[d] [1,3]-oxazin-2-one
• CAS NO: 305800-04-8
• Molecular Weight: 357.409
• Mol File: 305800-04-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(3-Benzoyl-phenyl)4,4-dimethyl-1,4-dihydro-benzo[d] [1,3]-oxazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(3-Benzoyl-phenyl)4,4-dimethyl-1,4-dihydro-benzo[d] [1,3]-oxazin-2-one(305800-04-8)
• EPA Substance Registry System: 6-(3-Benzoyl-phenyl)4,4-dimethyl-1,4-dihydro-benzo[d] [1,3]-oxazin-2-one(305800-04-8)

Safety Data

• Hazardous Substances Data: 305800-04-8(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 304853-36-9 3-(4,4-dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-3-yl)benzonitrile 

Relevant articles and documents

Cyclocarbamate derivatives as progesterone receptor modulators

This invention provides compounds of Formula (I): wherein R1 and R2 may be single substituents or fused to form spirocyclic or hetero-spirocyclic rings; R3 is H, OH, NH2, C1 to C6 alkyl, substituted C1 to C6 alkyl, C3 to C6 alkenyl, substituted C1 to C6 alkenyl, alkynyl, or substituted alkynyl, CORC; RC is H, C1 to C3 alkyl, substituted C1 to C3 alkyl, aryl, substituted aryl, C1 to C3 alkoxy, substituted C1 to C3 alkoxy, C1 to C3 aminoalkyl, or substituted C1 to C3 aminoalkyl; R4 is H, halogen, CN, NO2, C1 to C6 alkyl, substituted C1 to C6 alkyl, alkynyl, or substituted alkynyl, C1 to C6 alkoxy, substituted C1 to C6 alkoxy, amino, C1 to C6 aminoalkyl, or substituted C1 to C6 aminoalkyl; and R5 is selected from a trisubstituted benzene ring of a five or six membered ring with 1, 2, or 3 heteroatoms from the group including O, S, SO, SO2 or NR6 and containing one or two independent substituents from the group including H, halogen, CN, NO2, amino, and C1 to C3 alky, C1 to C3 alkoxy, C1 to C3 aminoalkyl, CORF, or NRGCORF; or pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions and methods using the compounds as antagonists of the progesterone receptor.