305841-29-6

Basic information

• Product Name: Sagopilone
• Synonyms: SAGOPILONE;(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-5-benzothiazolyl)-10-(2-propen-1-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione;De 03757;Unii-ky72ju32fo;Zk-epo;ZK 219477;BFZKMNSQCNVFGM-HQMJALQOSA-N
• CAS NO: 305841-29-6
• Molecular Formula: C30H41NO6S
• Molecular Weight: 543.71
• Mol File: 305841-29-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 711.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.153
• PKA: 13.53±0.70(Predicted)
• CAS DataBase Reference: Sagopilone(CAS DataBase Reference)
• NIST Chemistry Reference: Sagopilone(305841-29-6)
• EPA Substance Registry System: Sagopilone(305841-29-6)

Safety Data

• Hazardous Substances Data: 305841-29-6(Hazardous Substances Data)

Usage

Description

Sagopilone is a synthetic and experimental chemotherapeutic agent that belongs to the class of drugs known as epothilones, which are derived from a type of bacterium. It is characterized by its ability to disrupt the structure and function of microtubules in cancer cells, ultimately leading to cell death. Sagopilone has demonstrated promising results in preclinical and clinical studies for the treatment of various types of cancer, including breast cancer, non-small cell lung cancer, and ovarian cancer. However, due to its complex synthesis and potential side effects, further research is required to fully understand its therapeutic benefits and safety profile.

Uses

Used in Oncology:
Sagopilone is used as a chemotherapeutic agent for the treatment of various types of cancer. Its primary application is in the treatment of breast cancer, non-small cell lung cancer, and ovarian cancer. It works by targeting and disrupting the microtubules in cancer cells, which are essential for cell division and growth, ultimately leading to cell death.
Used in Cancer Research:
Sagopilone is also used in cancer research to study the effects of microtubule-targeting agents on cancer cells. Its complex synthesis and potential side effects make it an important subject for further research to better understand its therapeutic benefits and safety profile, as well as to explore possible improvements in its synthesis process and formulation to enhance its efficacy and reduce side effects.
Used in Drug Development:
In the pharmaceutical industry, Sagopilone serves as a candidate for drug development. Its unique mechanism of action and potential as a chemotherapeutic agent make it a valuable compound for the development of new cancer treatments. Researchers and pharmaceutical companies are interested in exploring its potential and optimizing its use in cancer therapy, as well as investigating possible combinations with other drugs to enhance its effectiveness and minimize side effects.