3062-48-4

Usage

Appearance

Pale yellow to dark brown liquid

Odor

Faint aromatic

Usage

Intermediate in the production of dyes, pharmaceuticals, and other organic compounds; chemical building block in the synthesis of various polymers and resins

Toxicity

Not highly toxic, but exposure to high concentrations may cause irritation to the skin, eyes, and respiratory system

Safety

Handle with care and follow proper safety protocols

InChI:InChI=1/C10H15NO2/c1-2-12-7-8-13-10-6-4-3-5-9(10)11/h3-6H,2,7-8,11H2,1H3

Upstream product

• 3062-47-3 2-nitrophenyl (2-ethoxyethyl) ether 
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• 176324-78-0 1-[2-(2-Iodo-ethoxy)-ethoxy]-2-nitro-benzene 

Relevant academic research and scientific papers

Synthesis of new dibenzo-diaza-crown ethers

A new method for the synthesis of dibenzo-diaza-crown ethers involving the 1:1-cyclocondensation of α,ω-contrafunctional amines is reported.

N-(N'-Methylenepyrrolidonyl)-2-substituted anilines

This invention relates to novel N-(N'-methylenepyrrolidonyl)-2-substituted anilines which are useful intermediates in the synthesis of herbicides. The intermediate compounds of the invention have the formula: STR1 Where R is alkyl, C1 -C6, alkenyl, C3 -C5, alkyleneoxyalkyl, --(CH2)n OR", where n=1-3, and R" is alkyl, C1 -C3, and cycloalkyl, STR2 where n'=0-3, R' is hydrogen or alkyl, C1 -C3, and, Y is oxygen or sulfur.

Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines

This invention relates to a process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines in high yield. The products are useful intermediates in the synthesis of herbicides. The process comprises reacting substantially equivalent molar concentrations of a 2-substituted aniline, as defined herein, with N-methylolpyrrolidone in an aromatic hydrocarbon solvent in the absence of an acid or base catalyst at a reflux temperature of 80°-140° C. while simultaneously and continuously distilling out from the reaction mixture an azeotrope consisting essentially of water and solvent until substantially all the water produced during the reaction has been removed thereby, and, thereafter, crystallizing the product from the remaining solution.

Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines

This invention relates to an improved process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines which are useful intermediates in the synthesis of agricultural herbicides. This process of the invention comprises reacting a 2-substituted aniline with N-chloromethylpyrrolidone at about room temperature in the presence of an acid acceptor. Such room temperature alkylation of the aniline prevents excessive side reactions, particularly with a substituent in the 2-position of the aniline, such as an alkenyl group, which is sensitive to alkylating agents which require excessive heating to effective the condensation reaction.

Herbicidal n-(haloacetyl)-n-(n-methylene pyrrolidonyl)-2-oxyalkyleneoxyalkylanilines

Herbicidal compounds having the formula: STR1 where n is 1-3, R is alkyl of 1-3 carbon atoms, R' is hydrogen or alkyl of 1-3 carbon atoms, and x is chloro or bromo, are disclosed herein. The compounds of the invention show good herbicidal activity, especi