306287-22-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 306287-20-7 (3S,4S)-1-phenylnon-8-en-1-yne-3,4-diol 
• 591-50-4 iodobenzene 
• 306287-11-6 (6S,7S)-6,7-(isopropylidenedioxy)-9-phenylnon-1-en-8-yne 
• 306287-16-1 (3S,4S)-1,1-dibromo-3,4-(isopropylidenedioxy)nona-1,8-diene 
• 306287-18-3 (6S,7S)-6,7-(isopropylidenedioxy)non-1-en-8-yne 
• 306287-14-9 (2S,3S)-2,3-(isopropylidenedioxy)oct-7-en-1-ol 

Relevant academic research and scientific papers

Pauson-Khand Reaction of Optically Active 6,7-Bis(tert-butyldimethylsiloxy)non-1-en-8-ynes

Treatment of (6S,7S)-7-bis(tert-butyldimethylsiloxy)non-1-en-8-ynes with dicobalt octacarbonyl gave the corresponding cobalt complex. This complex was subsequently exposed to the Pauson-Khand conditions in the presence of a promoter such as cyclohexylamine, thioanisole, methyl isopropyl sulfide, and butyl methyl sulfide ending up with the stereoselective production of the (2S,3S,6S,7S)-7-methylbicyclo[4.3.0]nonenone derivatives instead of the expected (2S,3S,7S)-bicyclo[5.3.0]decenone species.