306726-40-9

Upstream product

• 256342-01-5 (2S,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2-phenylselanyl-tetrahydro-pyran-3-ol 
• 256341-99-8 (3aR,4S,7R,7aS)-7-(4-Methoxy-benzyloxy)-2,2-dimethyl-4-phenylselanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran 
• 256342-00-4 (2S,3R,4R,5R)-5-(4-Methoxy-benzyloxy)-2-phenylselanyl-tetrahydro-pyran-3,4-diol 
• 256341-98-7 (3aR,4S,7R,7aS)-2,2-Dimethyl-4-phenylselanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 374115-40-9 phenyl 1-seleno-β-D-xylopyranoside 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 256341-86-3 tert-Butyl-[(3S,4S,5R)-2-fluoro-5-(4-methoxy-benzyloxy)-3-phenylselanyl-tetrahydro-pyran-4-yloxy]-dimethyl-silane 

Downstream Products

• 306726-42-1 C₅₅H₇₆O₁₄SeSi 
• 306726-37-4 C₅₆H₇₄O₁₆Si 
• 306726-36-3 C₄₉H₆₈O₁₇SSi 
• 306726-35-2 C₄₉H₇₀O₁₅Si 
• 306726-34-1 C₄₉H₆₈O₁₃Si 
• 306726-41-0 5-benzyloxy-6-(4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-4-[4-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-3-phenylselanyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-ol 

Relevant academic research and scientific papers

Total synthesis of everninomicin 13,384-1 - Part 2: Synthesis of the FGHA2 fragment

The stereoselective synthesis of everninomicin's 13,384-1 (1) FGHA2 fragment (2) in a suitable form for incorporation into the final target (1) is described. The construction of the FG 1,1′-disaccharide linkage relied on a new method based on tin-acetal chemistry, while for the GH orthoester bridge, a number of approaches were explored. Final success for the latter construction came when a novel 1,2-phenylseleno migration reaction was applied to couple rings G and H, followed by ketene acetal and orthoester formation.