306747-36-4

Basic information

• Product Name: (1R,2R)-2-(1-phenethyl-3-phenyl-prop-2-ynylamino)-2-phenyl-ethanol
• Synonyms: (1R,2R)-2-(1-phenethyl-3-phenyl-prop-2-ynylamino)-2-phenyl-ethanol
• CAS NO: 306747-36-4
• Molecular Weight: 355.48
• Mol File: 306747-36-4.mol

Chemical Properties

• CAS DataBase Reference: (1R,2R)-2-(1-phenethyl-3-phenyl-prop-2-ynylamino)-2-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-2-(1-phenethyl-3-phenyl-prop-2-ynylamino)-2-phenyl-ethanol(306747-36-4)
• EPA Substance Registry System: (1R,2R)-2-(1-phenethyl-3-phenyl-prop-2-ynylamino)-2-phenyl-ethanol(306747-36-4)

Safety Data

• Hazardous Substances Data: 306747-36-4(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 56613-80-0 D-2-phenylglycinol 
• 536-74-3 phenylacetylene 

Downstream Products

• 306747-42-2 (1R)-phenethyl-3-phenyl-prop-2-ynylamine 

Relevant articles and documents

Synthesis of enantiomerically pure α-substituted propargylic amines by reaction of organoaluminum reagents with oxazolidines

Various oxazolidines prepared in two steps from (R)-phenylglycinol react at 0 °C with dialkylalkynylalane-triethylamine complexes in the presence of trimethylaluminum in high yield and diastereoselectivity. Enantiomerically pure primary α-substituted propargylamines can be easily obtained in two steps after removal of ferrocenylmethyl protective group under smooth acidic conditions and oxidative cleavage of the chiral appendage.