306935-33-1 Usage
Uses
Used in Pharmaceutical Industry:
METHYL 2-CHLORO-4,4-DIMETHYL-3-OXOPENTANOATE is used as a chemical intermediate for the synthesis of various drugs. Its unique structure and properties allow it to be a key component in the development of new pharmaceutical compounds, contributing to the advancement of medicine.
Used in Agrochemical Industry:
In the agrochemical sector, METHYL 2-CHLORO-4,4-DIMETHYL-3-OXOPENTANOATE serves as an intermediate in the production of pesticides. Its reactivity and structural features make it suitable for the creation of effective pest control agents, thereby supporting agricultural productivity and crop protection.
It is crucial to handle METHYL 2-CHLORO-4,4-DIMETHYL-3-OXOPENTANOATE with care, as it is a potentially hazardous substance. Proper safety procedures should be followed during its use to ensure the well-being of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 306935-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,3 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 306935-33:
(8*3)+(7*0)+(6*6)+(5*9)+(4*3)+(3*5)+(2*3)+(1*3)=141
141 % 10 = 1
So 306935-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H13ClO3/c1-8(2,3)6(10)5(9)7(11)12-4/h5H,1-4H3
306935-33-1Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of thiazoles targeting flavivirus envelope proteins
Mayhoub, Abdelrahman S.,Khaliq, Mansoora,Kuhn, Richard J.,Cushman, Mark
scheme or table, p. 1704 - 1714 (2011/05/05)
A series of third-generation analogues of methyl 4-(dibromomethyl)-2-(4- chlorophenyl)thiazole-5-carboxylate (1), which had the most potent antiviral activity among the first- and second-generation compounds, have been synthesized and tested against yellow fever virus using a cell-based assay. The compounds were designed with the objectives of improving metabolic stability, therapeutic index, and antiviral potency. The biological effects of C4 and C5 substitution were examined. The methylthio ester and the dihydroxypropylamide analogues had the best antiviral potencies and improved therapeutic indices and metabolic stabilities relative to the parent compound 1.
HETEROARYLS AND THEIR USE AS PI3K INHIBITORS
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Page/Page column 288, (2010/08/18)
This invention provides compounds of formula (IA) or (IB): wherein R1, R2, G1 and HY are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
