306936-04-9

Basic information

• Product Name: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE
• Synonyms: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE;5-[2-Chloro-4-(trifluoromethyl)phenyl]-2-furaldehyde ,97%;5-(2-Chloro-4-(trifluoromethyl)phenyl)furan-2-carbaldehyde
• CAS NO: 306936-04-9
• Molecular Formula: C₁₂H₆ClF₃O₂
• Molecular Weight: 274.62
• Mol File: 306936-04-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 86 °C
• Boiling Point: 311.3°Cat760mmHg
• Flash Point: 142.1°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 0.000569mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE(306936-04-9)
• EPA Substance Registry System: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE(306936-04-9)

Safety Data

• Hazard Codes: T
• Statements: 36/37/38-43-25
• Safety Statements: 26-36/37/39-45-36/37-37/39
• Hazardous Substances Data: 306936-04-9(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

InChI:InChI=1/C12H6ClF3O2/c13-10-5-7(12(14,15)16)1-3-9(10)11-4-2-8(6-17)18-11/h1-6H

Upstream product

• 2689-65-8 5-iodofuran-2-carbaldehyde 
• 141738-80-9 2-chloro-1-iodo-4-(trifluoromethyl)benzene 
• 27329-70-0 5-formylfurane-2-boronic acid 
• 402-04-0 6-bromo-1-chloro-3-(trifluoromethyl)benzene 

Downstream Products

• 1400563-92-9 2-[5-(2-chloro-5-trifluoromethyl)-furan-2-ylmethylene]indan-1-one 

Relevant articles and documents

Preparation of Polyfunctional Organozinc Halides by an InX3- and LiCl-Catalyzed Zinc Insertion to Aryl and Heteroaryl Iodides and Bromides

A catalytic system consisting of InCl3(3 mol %) and LiCl (30 mol %) allows a convenient preparation of polyfunctional arylzinc halides via the insertion of zinc powder to various aryl iodides in THF at 50 °C in up to 95 % yield. The use of a THF/DMPU (1:1) mixture shortens the reaction rates and allows the preparation of keto-substituted arylzinc reagents. In the presence of In(acac)3(3 mol %) and LiCl (150 mol %), the zinc insertion to various aryl and heteroaryl bromides proceeds smoothly (50 °C, 2–18 h). Alkyl bromides are also converted to the corresponding zinc reagents in the presence of In(acac)3(10 mol %) and LiCl (150 mol %) in 70–80 % yield.