306950-81-2

Upstream product

• 600-00-0 ethyl 2-bromoisobutyrate 
• 5342-77-8 α-Nitro-2-methylpropionic acid ethyl ester 
• 34495-35-7 N-(1-ethoxycarbonyl-1-methylethyl)hydroxylamine 
• 52629-46-6 (2,4,6-trimethyl-phenyl)acetyl chloride 

Downstream Products

• 306950-83-4 ethyl 2-(N-mesitylacetyl-N-methoxymethoxyamino)-2-methylpropanoate 
• 306950-87-8 4-mesityl-1-methoxymethoxy-2,2-dimethyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl 3,3-dimethylbutanoate 
• 306950-86-7 1-hydroxy-4-mesityl-2,2-dimethyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl 3,3-dimethylbutanoate 
• 306944-57-0 4-hydroxy-3-mesityl-1-methoxymethoxy-5,5-dimethyl-1,5-dihydro-2H-pyrrol-2-one 

Relevant academic research and scientific papers

Synthesis of N-oxydihydropyrrole derivatives

N-Oxydihydropyrrole derivatives were synthesized through an intramolecular Claisen condensation reaction. The N-acylation of hindered hydroxylamines played a key role in providing the useful intermediates, which could be converted to a variety of N-oxydihydropyrrole derivatives.

Synthesis and Insecticidal Activity of N-Oxydihydropyrroles: 4-Hydroxy-3-mesityl-5,5-dimethyl Derivatives with Various Substituents at the 1-Position

A new series of N-oxydihydropyrrole derivatives was synthesized and evaluated for insecticidal activity against Nilaparvata lugens and Myzus persicae. Various substituents were introduced to the 1-position of the dihydropyrrole ring, and the derivatives obtained exhibited systemic and/or contact insecticidal activity. The structure-activity relationship revealed that small alkyoxy and alkoxyalkoxy groups were more favorable than alkylcarbonyloxy, alkoxycarbonyloxy, or sulfonyloxy groups as substituents at the 1-position.