30710-39-5Relevant academic research and scientific papers
A [3+2] cycloaddition-1,2-acyl migration-hydrolysis cascade for regioselective synthesis of 1,2,3-triazoles in water
Chakraborti, Gargi,Dash, Jyotirmayee,Mandal, Tirtha,Roy, Charles Patriot
supporting information, p. 7970 - 7973 (2021/08/17)
A cascade sequence involving [3+2] cycloaddition, 1,2-acyl migration and hydrolysis produces 2H-1,2,3-triazolesviathe regioselective formation ofN2-carboxyalkylated triazoles. The reaction proceeds in aqueous media through intriguing reaction kinetics using a CuI-prolinamide catalyst system. Prolinamide promotes the novel organocatalytic 1,2-acyl migration as well as hydrolysis of the resultingN2-carboxyalkylated triazoles.
Copper(I)-Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Azidoformates and Aryl Terminal Alkynes
Lee, Heejin,Lee, Jae Kyun,Min, Sun-Joon,Seo, Hyeonglim,Lee, Youngbok,Rhee, Hakjune
, p. 4805 - 4811 (2018/04/26)
The copper(I)-catalyzed azide-alkyne cycloaddition reaction has been extensively studied and widely applied in organic synthesis. However, the formation of 1,2,3-triazoles with electron-deficient azide has been a challenging problem. In this report, we ha
Method for catalytically synthesizing 1,2,3-triazole compound by copper acetate/hydroxylamine hydrochloride/sodium acetate catalytic system
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Paragraph 0014, (2017/12/29)
The invention discloses a method for catalytically synthesizing a 1,2,3-triazole compound by a copper acetate/hydroxylamine hydrochloride/sodium acetate catalytic system and belongs to the technical field of synthesis of the 1,2,3-triazole compound. The m
