30715-16-3Relevant academic research and scientific papers
Construction of Tropane Derivatives by the Organocatalytic Asymmetric Dearomatization of Isoquinolines
Xu, Jin-Hui,Zheng, Sheng-Cai,Zhang, Ji-Wei,Liu, Xin-Yuan,Tan, Bin
, p. 11834 - 11839 (2016)
A chiral-NHC-catalyzed highly diastereo- and enantioselective dearomatizing double Mannich reaction of isoquinolines was developed that provides a powerful and straightforward synthetic route toward substituted tropane derivatives with four contiguous ste
