30748-58-4

Basic information

• Product Name: 2-(4-fluoro-phenyl)-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester
• CAS NO: 30748-58-4
• Molecular Weight: 262.24
• Mol File: 30748-58-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-fluoro-phenyl)-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluoro-phenyl)-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester(30748-58-4)
• EPA Substance Registry System: 2-(4-fluoro-phenyl)-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester(30748-58-4)

Safety Data

• Hazardous Substances Data: 30748-58-4(Hazardous Substances Data)

Upstream product

• 2339-59-5 4-fluorobenzamidine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 30748-63-1 4-chloro-2-(4-fluoro-phenyl)-pyrimidine-5-carboxylic acid ethyl ester 

Relevant articles and documents

Novel inhibitors of AP-1 and NF-κB mediated gene expression: Structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate

In an effort to identify novel inhibitors of AP-1 and NF-κB mediated transcriptional activation, several analogues of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate (1) were synthesized and tested in two in vitro assays. The 2-(2'-thienyl) substituted compound (11) was identified as the most potent in this series. (C) 2000 Elsevier Science Ltd. All rights reserved.