307494-24-2Relevant articles and documents
Asymmetric cyclopropanation of styrene catalyzed by Cu-(chiral Schiff-base) complexes
Li, Zhengning,Liu, Guosheng,Zheng, Zhuo,Chen, Huilin
, p. 7187 - 7191 (2000)
Asymmetric cyclopropanation of olefins was carried out with chiral copper-Schiff base complexes derived from copper acetate monohydrate, substituted salicylaldehydes and a chiral amino alcohol. Substituents on salicylaldehyde framework demonstrate a significant effect on the steroselectivities. Those with electron-withdrawing properties enhance the selectivities, whereas bulky sustituents in ortho position to the phenol hydroxy group decrease the selectivities. An ee of more than 98% was achieved for the reaction of styrene with diazoacetate. (C) 2000 Elsevier Science Ltd.